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1、Active IngredientsLocal Brand NameMerck TCRoute of AdministrationFirst Priority DateFirst Product Patent Estimated ExpiryCAS Numberabacavir sulfateZIAGENAntiviral; Reverse Transcriptase InhibitorOral20-Jan-198820-Jan-2008188062-50-2acetaminophenACEPHENAnalgesic (Non-narcotic); AntipyreticOral;Rectal
2、;Other18-May-197903-Oct-2017103-90-2acetic acid glacialACETASOLOther;Vaginal;Otic20-Oct-199564-19-7adalimumabHUMIRAAntiarthritic/Antirheumatic; Anti-Inflammatory (Biological Response Modifier)Parenteral08-Apr-198301-Jan-2010331731-18-1albuminPLASMA-PLEXAntidote (Heavy Metal Poisoning)Parenteral;Topi
3、cal27-Jan-1983albuterolPROVENTILBronchodilator; Adrenergic Agonist (Beta-); TocolyticInhale23-Sep-196615-Feb-198918559-94-9albuterol sulfatePROVENTILBronchodilator; Adrenergic Agonist (Beta-); TocolyticInhale;Other;Oral23-Sep-196615-Feb-198951022-70-9alendronate sodiumFOSAMAXAntiosteoporotic; Bone R
4、esorption InhibitorOral28-Apr-198006-Feb-2008121268-17-5amlodipine besylateNORVASCAntihypertensive; Antianginal; Calcium Channel BlockerOral11-Mar-198231-Jan-2007111470-99-6amoxicillinAMOXILAntibacterial (Antibiotic)Oral23-Aug-196822-Mar-202061336-70-7anastrozoleARIMIDEXAntineoplastic (Hormonal); Ar
5、omatase InhibitorsOral16-Jun-198710-Jun-2008120511-73-1arginine hydrochlorideR-GENE 10Diagnostic AidOral;Parenteral;Other1119-34-2aripiprazoleABILIFYAntipsychotic; Dopamine-Serotonin System StabilizerOral;Parenteral30-Mar-197829-Mar-2005129722-12-9ascorbic acidVIT CVitamin/Vitamin SourceOral;Topical
6、;Parenteral;Other15-Jul-196450-81-7aspirin8-HOUR BAYERAntithrombotic; Analgesic (Non-narcotic); Anti-Inflammatory (Nonsteroidal); AntipyreticOral;Rectal31-Jul-198450-78-2atazanavir sulfateREYATAZAntiviral; HIV Proteinase InhibitorOral05-May-199209-Apr-2017229975-97-7atorvastatin calciumLIPITORAntili
7、pemic; HMG CoA Reductase InhibitorOral30-May-198624-Mar-2010134523-03-8azithromycinZITHROMAXAntibacterial (Antibiotic); AntiprotozoalOphthalmic;Parenteral;Other;Oral06-Mar-198101-Nov-2005117772-70-0beclomethasone dipropionateBECLOVENTGlucocorticoid; Antiallergic (Steroidal, Nasal); Antiasthmatic (St
8、eroidal, Inhalant); Anti-Inflammatory (Biological Response Modifier)Inhale;Other;Nasal23-Jul-195704-Apr-19845534-09-8benazepril hydrochlorideLOTENSINAntihypertensive; Ace-InhibitorOral11-Aug-198125-Sep-200186541-74-4betamethasoneCELESTONEGlucocorticoidOral21-May-198701-Mar-2016378-44-9betamethasone
9、acetateBETAMETHASONE ACEGlucocorticoidOther987-24-6betamethasone benzoateUTICORTGlucocorticoidTopical22298-29-9betamethasone dipropionateDIPROSONEGlucocorticoidTopical26-Oct-19765593-20-4betamethasone sodium phosphateCELESTONEGlucocorticoidParenteral151-73-5betamethasone valerateVALISONEGlucocortico
10、idTopical11-Jun-196304-Apr-19842152-44-5bevacizumabAVASTINAntineoplasticParenteral28-Dec-198829-Mar-2011216974-75-3biotinAPPEAREXVitamin/Vitamin SourceOral;Other13-Jun-197258-85-5bisoprolol fumarateZEBETAAntihypertensive; Adrenergic Blocker (Beta-)Oral09-Oct-197604-Oct-1997104344-23-2bortezomibVELCA
11、DEAntineoplasticParenteral28-Oct-199428-Oct-2014179324-69-7budesonideRHINOCORTGlucocorticoid; Antiasthmatic (Steroidal, Inhalant)Inhale;Other;Oral;Nasal19-May-197230-Dec-199251333-22-3buprenorphine hydrochlorideBUPRENEXAnalgesic (Narcotic)Oral;Parenteral05-Sep-196018-Mar-198653152-21-9bupropion hydr
12、obromideAPLENZINAntidepressant; Antiobesity AgentOral905818-69-1bupropion hydrochlorideWELLBUTRINAntidepressantOral04-Dec-196925-Jun-199131677-93-7caffeineALERTCNS Stimulant; DiureticOral;Other26-Apr-198358-08-2caffeine citrateCAFCITCNS StimulantOral;Parenteral;Other69-22-7caffeine sodium benzoateCA
13、FFEINE SOD BENZCNS StimulantParenteralcalciumACTICALOral;Other7440-70-2candesartan cilexetilATACANDAntihypertensive; Angiotensin II Receptor AntagonistOral01-Jan-191918-Apr-2011145040-37-5capecitabineXELODAAntineoplasticOral17-Nov-198713-Jan-2011154361-50-9carvedilolCOREGAntihypertensive; Adrenergic
14、 Blocker (Beta-)Oral13-Apr-197805-Sep-200772956-09-3carvedilol phosphateCOREG CRAntihypertensive; Adrenergic Blocker (Beta-)Oral610309-89-2ceftriaxone sodiumROCEPHINAntibacterial (Antibiotic)Other;Parenteral02-Apr-197714-Jul-1998104376-79-6celecoxibCELEBREXAnti-Inflammatory (Nonsteroidal); Cyclooxyg
15、enase-2 Inhibitor; AnalgesicOral22-Sep-199230-Nov-2013169590-42-5cetuximabERBITUXAntineoplasticParenteral08-Apr-198307-Jun-2015205923-56-4chlorpheniramine maleateANTAGONATEAntihistaminicOral;Parenteral04-Mar-1983113-92-8chlorpheniramine tannatePEDIATANAntihistaminicOralcholecalciferolVIT DVitamin/Vi
16、tamin SourceOral67-97-0ciprofloxacinCIPROAntibacterial (Synthetic)Parenteral03-Sep-198028-Oct-200385721-33-1ciprofloxacin hydrochlorideCIPROAntibacterial (Synthetic)Ophthalmic;Otic;Oral03-Sep-198028-Oct-200386393-32-0ciprofloxacin lactateCIPRO IVAntibacterial (Synthetic)Parenteral97867-33-9citric ac
17、idLaunched with generic nameOral;Other20-Oct-199877-92-9clarithromycinBIAXINAntibacterial (Antibiotic); AntiulcerativeOral04-Jun-198023-May-200581103-11-9clindamycin hydrochlorideCLEOCINAntibacterial (Antibiotic)Oral;Topical;Other08-Feb-196517-Feb-198721462-39-5clindamycin palmitate hydrochlorideCLE
18、OCINAntibacterial (Antibiotic)Oral25507-04-4clindamycin phosphateCLEOCIN PHOSPHATEAntibacterial (Antibiotic)Parenteral;Vaginal;Topical16-Dec-196630-Dec-198624729-96-2clopidogrel bisulfatePLAVIXAntithromboticOral13-Jul-198205-Jul-2003120202-66-6codeine phosphateCODEINEAnalgesic (Narcotic); Antitussiv
19、eOral;Parenteral;Other41444-62-6codeine sulfateCODEINE SULFAnalgesic (Narcotic); AntitussiveOral;Parenteral6854-40-6copperCU-7Parenteral27-Jan-20007440-50-8cyanocobalaminBERUBIGENHematopoietic; Vitamin/Vitamin SourceNasal;Parenteral;Other;Oral11-Feb-198368-19-9cyclosporineSANDIMMUNEImmunosuppressant
20、Ophthalmic;Parenteral;Other;Oral07-Mar-197824-Jul-200459865-13-3darbepoetin alfaARANESPHematopoieticParenteral13-Dec-198315-May-2024209810-58-2dexamethasoneAEROSEB-DEXDiagnostic Aid; Glucocorticoid; Antiallergic (Steroidal, Nasal); Antiasthmatic (Steroidal, Inhalant)Ophthalmic;Topical;Parenteral;Oth
21、er;Oral25-Nov-196002-Jun-201550-02-2dexamethasone acetateDECADRON-LADiagnostic Aid; Glucocorticoid; Antiallergic (Steroidal, Nasal); Antiasthmatic (Steroidal, Inhalant)Other;Parenteral55812-90-3dexamethasone sodium phosphateDECADRONDiagnostic Aid; Glucocorticoid; Antiallergic (Steroidal, Nasal); Ant
22、iasthmatic (Steroidal, Inhalant)Nasal;Parenteral;Other;Ophthalmic18-Apr-20082392-39-4dextroamphetamine sulfateDEXAMPEXCNS Stimulant; AnorexicOral23-Aug-199951-63-8dextromethorphanSCOT-TUSSIN DMAntitussive; AnalgesicOral17-Jun-1991125-71-3dextromethorphan hydrobromideHOLDAntitussive; AnalgesicInhale;
23、Topical;Other;Oral17-Jun-19916700-34-1dextromethorphan polistirexDELSYMAntitussive; AnalgesicOraldextromethorphan tannateAEROTUSS 12Antitussive; AnalgesicOraldextroseGLUCOSE OPHTHReplenishers/Supplements; AntihypoglycemicOphthalmic;Parenteral;Other;Oral27-Aug-199650-99-7dextrothyroxine sodiumCHOLOXI
24、NAntilipemic; Thyroid HormoneOral05-Nov-19917054-08-2diclofenac diethylamineVOLTAREN GELAnti-Inflammatory (Nonsteroidal)Topical78213-25-4diclofenac epolamineFLECTORAnti-Inflammatory (Nonsteroidal)Topical119623-66-4diclofenac potassiumCATAFLAMAnti-Inflammatory (Nonsteroidal)Oral15307-81-0diclofenac s
25、odiumVOLTARENAnti-Inflammatory (Nonsteroidal)Ophthalmic;Topical;Oral08-Apr-196526-Jan-198815307-79-6diltiazem hydrochlorideCARDIZEMAntihypertensive; Vasodilator (Coronary); Antianginal; Calcium Channel BlockerOral;Parenteral;Other28-Oct-196709-Feb-198833286-22-5docetaxel anhydrousTAXOTEREAntineoplas
26、ticParenteral17-Jul-198614-May-2010114977-28-5doconexentDHAOral6217-54-5donepezil hydrochlorideARICEPTNootropicOral22-Jun-198731-Mar-2009142057-77-0duloxetine hydrochlorideCYMBALTAAntidepressant; Serotonin Noradrenaline Reuptake Inhibitor (SNRI)Oral22-Dec-198611-Sep-2007136434-34-9dutasterideAVODART
27、Antiprostatic Hypertrophy; 5Alpha-Reductase InhibitorOral17-Sep-199317-Sep-2013164656-23-9efavirenzSUSTIVAAntiviral; Reverse Transcriptase InhibitorOral07-Aug-199207-Aug-2012154598-52-4emtricitabineEMTRIVAAntiviralOral01-Feb-199001-Feb-2010143491-57-0enalapril maleateVASOTECAntihypertensive; Ace-Inh
28、ibitorOral;Other11-Dec-197818-Sep-200176095-16-4enoxaparin sodiumLOVENOX (PRESERVATIVE FREE)AntithromboticParenteral679809-58-6epoetin alfaEPOGENHematopoieticParenteral29-Aug-2002113427-24-0ergocalciferolDELTALINVitamin/Vitamin SourceOral;Parenteral;Other12-Oct-200050-14-6erlotinib hydrochlorideTARC
29、EVAAntineoplasticOral30-Mar-199530-Mar-2015183319-69-9escitalopram oxalateLEXAPROAntidepressant; Serotonin Uptake InhibitorOral14-Jun-198808-Jun-2009219861-08-2esomeprazole magnesiumNEXIUMAntiulcerative; Gastric Secretion InhibitorOral04-Mar-198301-Mar-2008217087-09-7esomeprazole sodiumNEXIUM IVAnti
30、ulcerative; Gastric Secretion InhibitorParenteral04-Mar-198301-Mar-2008161796-78-7estradiolESTRACEEstrogenOral;Vaginal;Transdermal;Topical;Parenteral;Other16-Nov-197606-Mar-200750-28-2estradiol (17beta-)ESTRASORBEstrogenInhale;Transdermalestradiol acetateFEMRINGEstrogenOral;Other4245-41-4estradiol c
31、ypionateDEPO-ESTRADIOLEstrogenOral;Parenteral;Other313-06-4estradiol valerateDELESTROGENEstrogenOral;Parenteral;Other05-Aug-1983979-32-8estrogens conjugatedPREMARINEstrogenOral;Vaginal;ParenteraletanerceptENBRELCardiotonic; Antidiabetic; Analgesic (Non-narcotic); Immunosuppressant; Antiarthritic/Ant
32、irheumatic; Antipsoriatic; Anti-Inflammatory (Biological Response Modifier)Parenteral25-Feb-198005-Sep-2009185243-69-0ethinyl estradiolESTINYLEstrogen; Contraceptive (Oral)Oral24-Jul-197528-Mar-199557-63-6ezetimibeZETIAAntilipemicOral09-Jul-199321-Mar-2014163222-33-1fenofibrateLIPIDILAntilipemicOral
33、31-Jan-196923-Sep-199249562-28-9fentanylDURAGESIC-100Analgesic (Narcotic)Transdermal21-Apr-198323-Jul-2004437-38-7fentanyl citrateSUBLIMAZE PRESERVATIVE FREEAnalgesic (Narcotic)Oral;Parenteral;Other21-Apr-198323-Jul-2004990-73-8ferrous fumarateFEOSTATHematinicOral141-01-5ferrous gluconateFERROUS GLU
34、CHematinicOral12389-15-0ferrous sulfateFER-IN-SOLHematinicOral7782-63-0fexofenadine hydrochlorideALLEGRAAntihistaminicOral10-Apr-197910-Apr-1999138452-21-8filgrastimNEUPOGEN(OLD)Hematopoietic; AntineutropenicParenteral04-Nov-197428-Mar-2005121181-53-1finasteridePROSCARAntineoplastic; Antialopecia Ag
35、ent; Antiprostatic Hypertrophy; 5Alpha-Reductase Inhibitor; AntifungalOral13-Apr-197813-Apr-199898319-26-7fluticasone propionateCUTIVATEGlucocorticoid; Antiallergic (Steroidal, Nasal); Antiasthmatic (Steroidal, Inhalant); Anti-Inflammatory (Biological Response Modifier)Inhale;Topical;Nasal15-Feb-198
36、025-Mar-200380474-14-2folic acidFOLICETVitamin/Vitamin SourceOral;Parenteral;Other17-Oct-199559-30-3formoterol fumarateFORADILBronchodilator; Adrenergic Agonist (Beta-); AntiasthmaticInhale05-Feb-197230-Nov-199343229-80-7gabapentinNEURONTINAntipsychotic; Analgesic (Non-narcotic); Antidepressant; Ant
37、imigraine; AnticonvulsantOral;Other21-Dec-197417-May-199460142-96-3gemcitabine hydrochlorideGEMZARAntineoplasticParenteral10-Mar-198310-Mar-2003122111-03-9ginsengCOLD FXOralglatiramer acetateCOPAXONEImmunomodulator; NeuroprotectiveParenteral21-Apr-197124-May-2014147245-92-9glimepirideAMARYLAntidiabe
38、ticOral19-Dec-197906-Oct-200593479-97-1glutamic acid hydrochloride (l-)GLUTAMIC ACID HCLAnxiolytic; Replenishers/Supplements; AcidifierOral138-15-8glycine (l-)AMINOACETIC ACID 1.5% IN PLASTIC CONTAINERAntipruriticOther;Parenteral56-40-6guaifenesinMUCINEXExpectorant; Muscle RelaxantOral25-Feb-198193-
39、14-1hyaluronic acidRESTYLANEAntiarthritic/AntirheumaticParenteral07-Apr-192016-May-20089004-61-9hydrochlorothiazideESIDRIXAntihypertensive; DiureticOral25-Sep-196429-Dec-198158-93-5hydrocortisoneACTICORTGlucocorticoid; Anti-Inflammatory (Biological Response Modifier)Oral;Topical;Rectal;Other29-Mar-1
40、97850-23-7hydrocortisone 17-butyrateLOCOIDGlucocorticoidTopical13609-67-1hydrocortisone acetateCORTEF ACETATEGlucocorticoidOral;Topical;Rectal;Parenteral;Other50-03-3hydrocortisone cypionateCORTEFGlucocorticoidOral508-99-6hydrocortisone sodium phosphateHYDROCORTONEGlucocorticoidParenteral6000-74-4hy
41、drocortisone sodium succinateA-HYDROCORTGlucocorticoidParenteral125-04-2hydrocortisone valerateWESTCORTGlucocorticoidTopical57524-89-7ibandronate sodiumBONIVABone Resorption InhibitorOral;Parenteral11-Jul-198617-Jul-2007138926-19-9ibuprofenIBUAnti-Inflammatory (Nonsteroidal)Oral;Parenteral;Other02-F
42、eb-196128-May-198515687-27-1ibuprofen lysineNEOPROFENAnti-Inflammatory (Nonsteroidal); AnalgesicParenteral57469-77-9icosapentEPA NAT FISH OILAntilipemicOral27-Jan-199310417-94-4imatinib mesylateGLEEVECAntineoplasticOral03-Apr-199215-Sep-2014220127-57-11immune globulin intravenous (human)IMMUNE GLOBU
43、LINImmunizing Agent - PassiveParenteral04-Oct-2001infliximabREMICADEAntiviral; Immunosuppressant; Anti-Inflammatory (Gastrointestinal); Anti-Inflammatory (Biological Response Modifier)Parenteral08-Apr-198301-Jan-2010170277-31-3influenza A (H1N1) 2009 monovalent vaccineINFLUENZA A (H1N1)Nasal;Parenteral15-Sep-2000influenza virus vaccine inactivated surface antigenINFLUENZA VIR VACImmunizing Agent - ActiveNasal;Parenteral