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1、腐植酸钠（Humic acid sodium）Information on humic acid sodium replication linkDragon city fly will send short message to the friend dragon city to fly the current offline integral 14993 UID35 reading authority 255 online time 3658 hours BBS: 30591 yuan in 2011-6-12.Super moderatorWriting brush: round turn
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3、the domestic and foreign practice has proved that humic acid is not only a good biological growth hormone, but also a kind of widely used drugs. Humic acid composition, has not yet entirely clear, known humic acid molecule containing benzene ring, fused ring, and some heterocyclic (e.g., pyrrole, fu
4、ran, indole, etc.), the aromatic ring connected with the key bridge, there are various functional groups on the aromatic ring, mainly is the carboxyl group, phenolic hydroxyl, methoxy, quinone, etc. Because humic acid has such a complex molecular structure, it is possible to show a variety of chemic
5、al properties of the 1. For example, due to the larger molecular weight of humic acid itself, it is possible to synthesize larger particle 1 in a certain medium and thus have the properties of colloids and adsorption capacity. Humic acid molecules, there are many carboxylic and phenolic hydroxyl, so
6、 has the weak acid, indeed, strong ability of ion exchange and chelating ability and the buffering capacity: humic acid molecules on phenol, quinone structure, biological oxidation reduction may be involved in electronic messaging system. These physical and chemical properties may also affect the fu
7、nction of biological macromolecules, which may result in physiological and pharmacological activities. In this paper, we review the research progress of humic acid sodium.I. promotion: the activation and absorption of feed ingredientsDue to the ability of the colloidal properties and adsorption of t
8、he chemical molecules of humic acid, good ion exchange and catalytic action have been formed, and the activation and absorption of feed ingredients are now in seven aspects:1. To decompose the various complex molecular nutrients in the feed and to make good organic combination, increase gastrointest
9、inal digestion and promote protein assimilation.2. Improve the permeability of animal cell membrane and protoplasm, and increase the gap between muscle cells and the water content of the cells.3. The adsorption of humic acid, which makes the feed nutrient slow from the spoon through the intestines,
10、enhances the absorption of digestion time and improves the absorption rate of nutrients.4. Humic acid molecules are rich in nitrogen, and amino has strong absorption, it makes the ammoniation of protein content in the feed to make full use of, high limit into muscle protein feed protein, reach muscl
11、e growth potential, increase the proportion of lean meat.5. The base of humic acid contains quinones, which participate in the process of oxidation and reduction of the body, so that the metabolism is strong, and the cell proliferation and growth are accelerated.6. Sodium humate has convergent effec
12、t because of the coagulation effect of sodium humate. According to the experimental results, sodium humate was five times higher than that of tannin. When humic acid comes into the body,Can strengthen the activity of a variety of enzyme, promote oxidation reduction and metabolism.7. Since humic acid
13、 sodium can promote digestion and absorption, the mineral elements in the feed compatibility can be better absorbed and utilized to make full use of the mineral elements and multivitamins.Second, the effect of endocrine functionHumic acid can be by stimulating certain glands, inhibiting sympathetic
14、nerve, cause drowsiness, carcass in a state of sleep or quiet time increased, the whole body movement and visceral activities generally decreases, which is advantageous to the assimilation of the whole body, the function of each organ system can recover in time, the other - hypothermia during sleep,
15、 the movement of heat loss and excess to reduce energy consumption, relative can increase the storage, thus increase the precipitation amount of muscle, fat, improve the feed conversion rate.Zheng ping reported that humic acid can significantly increase the weight of the adrenal gland, and the conte
16、nt of ascorbic acid and thymic acid can promote the function of the adrenal cortex. According to liu, huangsaic acid in gongxian can increase the concentration of plasma cortisol in rabbits, thus enhancing the emergency response and resistance.The blood sugar levels were significantly higher after t
17、he rabbits were injected with peat humic acid in the abdomen. The increase in blood sugar begins at 1 hour, reaches a peak of 2 hours, lasts 4 to 5 hours, and has a dependent relationship.Beijing yellow rot acid can reduce the free fatty acid concentration in rabbit plasma and has a dose-dependent r
18、elationship. This effect is not interrupted by atropine, nor is it accompanied by changes in insulin levels, which are not affected by propranolol, but can be antagonized by receptor blockers. It is suggested that yellow rot may inhibit the secretion of glucagon by stimulating alpha receptors, leadi
19、ng to a decrease in the concentration of free fatty acids.3. Anti-inflammatory effectAccording to the report, there are a lot of reports on the study of the anti-inflammatories of humic acid, and the results show that most humic acid has anti-inflammatory effects. Humic acid can inhibit and kill pat
20、hogenic bacteria in the intestinal tract, purify the gastrointestinal environment, and from the practice of breeding, the experimental group basically does not have diarrhea, and the prevention and control effect of the gastrointestinal card is also obvious.According to the report of animal husbandr
21、y and veterinary station in aksu district in xinjiang, it is reported that the pre-production or long-term feeding of humic acid sodium in the sow can make the piglets have a strong resistance to the intestinal bacteria.Baicheng county in xinjiang animal husbandry and veterinary station, through the
22、 lamb flow field trials show that treatment, humic acid sodium is the lamb diarrhea curative effect is good, mainly it for polymer complex, and contain alkaloids, reason for intestinal inflammatory and toxic substances have strong adsorption capacity, at the same time have convergent effect to the i
23、ntestinal mucosa, due to the structure of sodium humate contains various active group, which could shrink blood vessels, lower blood capillary permeability, antiphlogistic hemostatic effect, but most importantly, humic acid sodium has the ability to enhance antibody immune.Wang zhongxin has proved t
24、hat humic acid is different from antibiotics and is not dissociated by mold and bacteria, and can make viral protein degeneration, so it has anti-virus effect.Wang zongrui has proved that the humic acid of the lian jiang river has obvious anti-inflammatory effect on the egg white and formaldehyde of
25、 the rat. The white blood cells induced by the injection of carboxymethyl cellulose in the subcutaneous airbags;There was a significant inhibitory effect on the growth of granulation tissue, suggesting that humic acid had an effect on the exudates and proliferation of inflammation(abdominal or thora
26、cic contact with external contact, leakage of the intestinal canal, excessive bleeding) resulting in death, and no death from other skin and skin injuries. Tip: sodium humate has a significant effect on the healing of chicken pecking.Wang jinggui reports that peat humic acid sodium has the effect of
27、 accelerating tissue regeneration, which can promote the healing of experimental gastric ulcer in rats. According to the report, Beijing yellow rot and brown acid can promote the healing of skin wounds in rats, significantly increasing its tensile strength, and the effect is dependent on dose.R, yan
28、qing humic acid of pyloric ligation in rats, limit the cold stress, chronic gastric ulcer acetate have obvious protective effect, lavage or injected medicine effectively, and injected effect better, effect and dose dependent.5. Influence on the function of circulating systemThe effect of huangsaicic
29、 acid on the microcirculation of cheek sac in golden state was studied by an automatic measurement system of microvasculature. After the addition of norepinephrine, the diameter, velocity and flow of capillaries were reduced to zero. The average velocity and aperture of the microartery; With half th
30、e normal, microvenous spasm is lighter than the microarterial. After the local application of yellow saproic acid, the effect of norepinephrine can be quickly antagonistic, the microarterial spasm is relieved, the flow rate is obviously accelerated, and the blood flow is increased. The effect of cap
31、illary was also significant, but it was 3-5 minutes longer than the microarterial delay. The function of microveins is weak. Tip: yellow rot acid has alpha beta blocker.Han qide reported that in the early stage of the rat coronary artery ligation, the application of Beijing yellow rot acid could sig
32、nificantly reduce the infarction area of the two days after ligation and significantly improve myocardial contractility. The direct expression of yellow rot to the left ventricular hemodynamics is: aortic pressure and indoor pressure increase, the left ventricular myocardial constriction is enhanced
33、, the heart rate is accelerated. In the case of decreased myocardial contraction in the left ventricle, yellow saproic acid has a strong heart function, and the effect size is closely related to the degree of cardiac failure.6. Influence of coagulation functionLiu yaoxiang reported that the yellow r
34、ot of gongxian can shorten the blood clotting time in vitro and also significantly shorten the time of liver bleeding in rats, which can be compared with that of yunnan baiyao. Yao Fa industry reports, turpan fulvic acid injected, can make the cut end shorten the bleeding time of mice, also increase
35、 the number of peripheral blood platelet juice, can make the in vitro rabbit blood clotting time significantly shortened, the toad mesenteric vessels have obvious effect. Someone use can automatically record the speed of the whole process of blood coagulation and blood coagulation consistence stretc
36、h bending of thrombosis figure (TEC) to explore the hemostatic effect and mechanism of ligou fulvic acid, prove the mobilization of fulvic acid in vivo clotting factors involved in the coagulation effect quickly.Li Shengqi reports, datong fulvic acid in rats and rabbits in vitro thrombus formation,
37、have obvious inhibition, thrombus length and dry weight were lower than the control group (by inhibiting platelet aggregation and anticoagulant).Vii. Effects on immune functionThere are many studies on the immune function of humic acid in animals, which are summarized in the following aspects:1. Hum
38、ic acid can increase the weight of spleen in mice and rabbits.The white - medullary region is enlarged, the red - medullary lymphocyte is significantly increased, and there are large macrophages, hint: the function of the immune organ is promoted.2. The function of reticuloendothelial system is also
39、 known as the excitation of non-specific immune function.3. Yellow rot has no effect on cellular immunity.4. Rhubaric acid can promote the increase of cell proliferation in the spleen cells of the animal with the immunological ability of erythrocytes. Tip: yellow humic acid has the effect of enhanci
40、ng humoral immunity.5. Lian jiang humic acid significantly inhibited the reaction of rabbit skin hypersensitivity (PCA), but the effect of the isolated ileum in guinea pig was not able to fight the allergic media (histamine, 5 hydroxytryptamine, etc.).Viii. Others1. The king in your reports, with ad
41、ded urea feed feed cows, often occur poisoning, and the experimental group after long-term and feed sodium humate, urea poisoning phenomena do not occur, and greatly reduce the faeces of bad smell. Tip: humic acid sodium adsorption of urea by rumen microbes in the elimination of excess ammonia and u
42、rea to both buffer livestock poisoning effect, and absorbed by sodium humate ammonia can also be in the rumen microbes use, improve the efficiency of urea. Meanwhile, in the process of digestion, the ammonia in the stool reduces the smell of feces. Li Zhongguang through the open laying house, determ
43、ination of the concentration of harmful gas in brood hen house shows that adding humic acid compound additive group, ammonia content can reduce 41.67 54.60% than the control group, the oxidation of carbon reduction of 51.26 61.22%, hydrogen sulfide is significantly reduced, further provedSodium huma
44、te can neutralize ammonia, carbon monoxide and hydrogen sulfide in animal bodies.2. Li zhongxing, by adding humic acid sodium to his chickens, found that the content of the content and the number of red blood cells were higher than the control group. The authors suggest that sodium humate may have t
45、he effect of promoting Hb synthesis and erythrocyte formation.3. Su Bingwen report, with 2% 2% of the total humic acid sodium and sodium humate chicken embryo allantoic injection, dose of 50 mg/kg and 25 mg/kg, did not cause adverse impact of the growth of embryo sac and no significant difference on the output rate of the young, the external form and creations no distortion of viscera and toxic effects.