Cells of inflammation and Immunity:炎症和免疫细胞.ppt

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1、Cells of inflammation and Immunity,G. Wharfe 2005,Immune system,Detect and respond to antigens Protects against pathogenic microorganisms Also elicits response against noninfectious foreign organisms Used in inflammatory response and tissue repair,Immune response,Response needs to be quick and effic

2、ient Two systems Innate Adaptive,Cells of IR,All derived from BM stem cells Influenced by growth factors Begin as multipotent stem cell Develop into committed stem cells,Innate immune system,First to respond Limits infection before adaptive response Usually involve nonlymphoid cells Cells are macrophages and polymorphonuclear neutrophils(PMN) Also involves complement and acute phase proteins If innate immunity cures infection-no adaptive immunity develops,Normal haematopoiesis,

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