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1、肝脏瞬时弹性超声评价自身免疫性肝炎肝纤维化的价值王绮夏;沈镭;丘陵凯;包瀚;陈晓宇;普民德;茅益民;马雄【期刊名称】中华肝脏病杂志【年(卷)，期】2011(019)010【摘要】Objective To validate transient elastography (Fibroscan) in assessment of hepatic fibrosis in autoimmune hepatitis (AIH).Methods Liver stiffness was assessed using Fibroscan in totally 30 patients with AIH.We co
2、mpared the results of Fibroscan with the Scheuer fibrosis stage in liver biopsy in each patie nt Results 4 patients were shown as liver fibrosis stage SO,6 as S 1,5 as S2zll as S3 and 4 as S4.Failure of the Fibroscan measurement occurred in 1 case (33 %) because of her increased body mass index (BMI
3、).The stiffness of Fibros can was significantly correlated with the liver biopsy fibrosis stage (r= 0.801.P 0.001).The liver stiffnesses between mild and moderate fibrosis (SO-2) and advaneed fibrosis (S3-4) were significantly different (t=-3.937,P 二 0.001).Conclusion Transient elastography (Fibrosc
4、an) is a promising non-invasive method for detection of fibrosis in patients with autoimmune hepatitis.Its use for the follow up and management of these patients and should be evaluated further.%的验证肝脏瞬时弹性 超声在评 估自身免疫性肝炎(AIH)患者肝纤维化程度中的价值,方法用瞬时弹性 超声对30 例AIH患者进行肝脏瞬时弹性测定，并将测定值与按照Scheuer系统进行纤维 化分级的患者肝活组织检查结果作纤维化程度的1：匕较，用Spearman等