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1、最大限度地展示您的研究成果 英语医学论文写作实例分析 张科宏博士 长青藤编辑总裁 同济大学生命科学院兼职教授 Tel: 021-51370992 E-mail: Website: www.ivy-,www.ivy-,论文核心内容 1）标题 2）摘要 3）正文,E-mail: ; Tel: 02151370992,www.ivy-,论文核心内容 1）标题 目的：在第一时刻抓住读者审稿人的目光,www.ivy-,E-mail: ; Tel: 02151370992,论文核心内容 1）标题 目的：在第一时刻抓住读者审稿人的目光 技巧：把主要研究结果 “装入” 标题,www.ivy-,E-mail:
2、 ; Tel: 02151370992,论文核心内容 1）标题 2）摘要 目的：吸引读者审稿人引入正文,www.ivy-,E-mail: ; Tel: 02151370992,论文核心内容 1）标题 2）摘要 目的：吸引读者审稿人引入正文 技巧：给出一个完整的“故事梗概”,www.ivy-,E-mail: ; Tel: 02151370992,论文核心内容 1）标题 2）摘要 3）正文 目的：将一个完整的 “故事” 呈现给读者,www.ivy-,E-mail: ; Tel: 02151370992,论文核心内容 1）标题 2）摘要 3）正文 目的：将一个完整的 “故事” 呈现给读者 技巧：换位
3、思维，撰写稿件时以读者为中心,www.ivy-,E-mail: ; Tel: 02151370992,常见问题,www.ivy-,E-mail: ; Tel: 02151370992,The current study is the randomized, placebo-controlled clinical trial.,www.ivy-,E-mail: ; Tel: 02151370992,www.ivy-,E-mail: ; Tel: 02151370992,www.ivy-,The current study is the randomized, placebo-controlled
4、 clinical trial.,E-mail: ; Tel: 02151370992,The current study is a randomized, placebo- controlled clinical trial.,www.ivy-,The current study is the randomized, placebo-controlled clinical trial.,E-mail: ; Tel: 02151370992,冠词运用不当,www.ivy-,E-mail: ; Tel: 02151370992,International Journal of Radiation
5、 Oncology Biology Physics, 67:888-896, 2007 Due to the complex molecular pathogenesis of glioblastoma multiforme, therapeutic strategies are evolving from cytotoxic therapies to molecular approaches which target specific signaling cascades that promote tumor growth such as cyclooxygenase-2 (COX-2),
6、a rate-limiting enzyme in conversion of arachidonic acid into prostaglandins.,www.ivy-,E-mail: ; Tel: 02151370992,International Journal of Radiation Oncology Biology Physics, 67:888-896, 2007 Due to the complex molecular pathogenesis of glioblastoma multiforme, therapeutic strategies are evolving fr
7、om cytotoxic therapies to molecular approaches which target specific signaling cascades that promote tumor growth such as cyclooxygenase-2 (COX-2), a rate-limiting enzyme in conversion of arachidonic acid into prostaglandins.,www.ivy-,E-mail: ; Tel: 02151370992,International Journal of Radiation Onc
8、ology Biology Physics, 67:888-896, 2007 Due to the complex molecular pathogenesis of glioblastoma multiforme, therapeutic strategies are evolving from cytotoxic therapies to molecular approaches which target specific signaling cascades that promote tumor growth such as cyclooxygenase-2 (COX-2), a ra
9、te-limiting enzyme in conversion of arachidonic acid into prostaglandins.,www.ivy-,E-mail: ; Tel: 02151370992,International Journal of Radiation Oncology Biology Physics, 67:888-896, 2007 Due to the complex molecular pathogenesis of glioblastoma multiforme, therapeutic strategies are evolving from c
10、ytotoxic therapies to molecular approaches which target specific signaling cascades that promote tumor growth such as cyclooxygenase-2 (COX-2), a rate-limiting enzyme in conversion of arachidonic acid into prostaglandins.,www.ivy-,E-mail: ; Tel: 02151370992,International Journal of Radiation Oncolog
11、y Biology Physics, 67:888-896, 2007 Due to the complex molecular pathogenesis of glioblastoma multiforme, therapeutic strategies are evolving from cytotoxic therapies to molecular approaches which target specific signaling cascades that promote tumor growth such as cyclooxygenase-2 (COX-2), a rate-l
12、imiting enzyme in conversion of arachidonic acid into prostaglandins.,www.ivy-,E-mail: ; Tel: 02151370992,理解困难的超长复合句,www.ivy-,E-mail: ; Tel: 02151370992,The frequency of the 03 allele of the DRB1 gene in the hepatitis B and hepatitis C groups was significantly higher than the controls. However, the
13、allele frequency of DRB1-15 in the chronic hepatitis B/C groups was lower than the controls.,www.ivy-,E-mail: ; Tel: 02151370992,The house is big enough. （） I dont like its location.,房子够大，（）我不喜欢它的地点。,www.ivy-,E-mail: ; Tel: 02151370992,The earth has relatively little iron. () this newly discovered p
14、lanet contains more iron than any other element.,地球含铁量很小。（）这个新发现的行星含铁高于任何其他元素。,www.ivy-,E-mail: ; Tel: 02151370992,The earth has relatively little iron. This newly discovered planet, in contrast, contains more iron than any other element.,地球含铁量很小。这个新发现的行星则相反，含铁高于任何其他元素。,www.ivy-,E-mail: ; Tel: 02151
15、370992,The frequency of the 03 allele of the DRB1 gene in the hepatitis B and hepatitis C groups were significantly higher than the controls. However, the allele frequencies of DRB1-15 in the chronic hepatitis B/C groups were lower than the controls.,www.ivy-,E-mail: ; Tel: 02151370992,The frequency
16、 of the 03 allele of the DRB1 gene in the hepatitis B and hepatitis C groups were significantly higher than the controls. However, the allele frequencies of DRB1-15 in the chronic hepatitis B/C groups were lower than the controls.,. The allele frequency of DRB1-15 in the chronic hepatitis B/C groups
17、, in contrast, was lower than the controls.,www.ivy-,E-mail: ; Tel: 02151370992,科学逻辑表述不正确,www.ivy-,E-mail: ; Tel: 02151370992,International Journal of Radiation Oncology Biology Physics, 67:888-896, 2007 Due to the complex molecular pathogenesis of glioblastoma multiforme, therapeutic strategies are
18、 evolving from cytotoxic therapies to molecular approaches which target specific signaling cascades that promote tumor growth such as cyclooxygenase-2 (COX-2), a rate-limiting enzyme in conversion of arachidonic acid into prostaglandins.,www.ivy-,E-mail: ; Tel: 02151370992,www.ivy-,Despite of the co
19、mplex molecular pathogenesis of glioblastoma multiforme, therapeutic strategy are evolving from cytotoxic therapies to molecular approaches. Activation of cyclooxygenase-2 (COX-2), the rate-limiting enzyme in prostaglandin biosynthesis, promotes tumor growth, and therefore represents a promising tar
20、get for intervention.,Due to the complex molecular pathogenesis of glioblastoma multiforme, therapeutic strategies are evolving from cytotoxic therapies to molecular approaches which target specific signaling cascades that promote tumor growth such as cyclooxygenase-2 (COX-2), a rate-limiting enzyme
21、 in conversion of arachidonic acid into prostaglandins.,E-mail: ; Tel: 02151370992,www.ivy-,Recent evidence suggests that interleukin-17 may play a putative role in innate immunity.,E-mail: ; Tel: 02151370992,www.ivy-,Recent evidence suggests that interleukin-17 may play a putative role in innate im
22、munity.,E-mail: ; Tel: 02151370992,www.ivy-,Recent evidence suggests that interleukin-17 may play a putative role in innate immunity.,Interleukin-17 has recently been implicated in innate immunity.,E-mail: ; Tel: 02151370992,www.ivy-,概念表述重复,E-mail: ; Tel: 02151370992,www.ivy-,Results In order to exa
23、mine the effects of sitagliptin on glucose level, diabetic rats were treated with various doses of sitagliptin. The blood glucose level was significantly different between the H and M groups compared with the C group. The L group was not statistically different from the C group.,E-mail: ; Tel: 02151
24、370992,www.ivy-,Results In order to examine the effects of sitagliptin on glucose level, diabetic rats were treated with various doses of sitagliptin. The blood glucose level was significantly different between the H and M groups compared with the C group. The L group was not statistically different
25、 from the C group.,E-mail: ; Tel: 02151370992,www.ivy-,Results In order to examine the effects of sitagliptin on glucose level, diabetic rats were treated with various doses of sitagliptin. The blood glucose level was significantly different between the H and M groups compared with the C group. The
26、L group was not statistically different from the C group.,E-mail: ; Tel: 02151370992,www.ivy-,Results In order to examine the effects of sitagliptin on glucose level, diabetic rats were treated with various doses of sitagliptin. The blood glucose level was significantly different between the H and M
27、 groups compared with the C group. The L group was not statistically different from the C group.,E-mail: ; Tel: 02151370992,www.ivy-,Results In order to examine the effects of sitagliptin on glucose level, diabetic rats were treated with various doses of sitagliptin. The blood glucose level was sign
28、ificantly different between the H and M groups compared with the C group. The L group was not statistically different from the C group.,Results Sitagliptin significantly decreased blood glucose concentration in diabetic rats at 10 and 20 mg/kg/d, but not at a lower dose of 5 mg/kg/d.,E-mail: ; Tel:
29、02151370992,www.ivy-,概念表述不到位不具体 描述 “ 不友好 ”（干预分组缩写）,E-mail: ; Tel: 02151370992,An anti-ErbB2 antibody reverses resistance of breast cancer cells to paclitaxel by down-regulating Akt/NFB,www.ivy-,E-mail: ; Tel: 02151370992,Paclitaxel is the drug of choice with significant anti-tumor activity towards b
30、reast cancer, ovarian cancer, cervical cancer, among others. However, the success of paclitaxel in the treatment of advanced or drug-resistant breast cancers is limited because of largely associated highly non-specific cytotoxicity. Furthermore, there is no specific treatment for metastasis that fol
31、lows surgery, radiotherapy, and chemotherapy. Tumors tend to acquire resistance to chemotherapeutic agents, including paclitaxel. Akt is suggested to be involved in chemoresistance.,www.ivy-,E-mail: ; Tel: 02151370992,www.ivy-,An anti-ErbB2 antibody reverses resistance of breast cancer cells to pacl
32、itaxel by down-regulating Akt/NFB,E-mail: ; Tel: 02151370992,www.ivy-,An anti-ErbB2 antibody reverses resistance of breast cancer cells to paclitaxel by down-regulating Akt/NFB 1）paclitaxel 是治疗乳腺癌的首选药 2）癌细胞长期暴露于 paclitaxel 产生耐药 3）乳腺癌耐药的主要机理 4）ErbB2 Akt/NFB 通路和耐药的关系,E-mail: ; Tel: 02151370992,Paclita
33、xel is the drug of choice with significant anti-tumor activity towards breast cancer, ovarian cancer, cervical cancer, among others. However, the success of paclitaxel in the treatment of advanced or drug-resistant breast cancers is limited because of largely associated highly non-specific cytotoxic
34、ity. Furthermore, there is no specific treatment for metastasis that follows surgery, radiotherapy, and chemotherapy. Tumors tend to acquire resistance to chemotherapeutic agents, including paclitaxel. Akt is suggested to be involved in chemoresistance.,www.ivy-,E-mail: ; Tel: 02151370992,概念层次多余不合理,
35、www.ivy-,E-mail: ; Tel: 02151370992,Wang et al., Neuroscience Letters 382:236-241, 2005 Acupuncture, a pearl in the Traditional Chinese Medicine, has been shown to bring about functional recovery after spinal cord injury, it has been widely used by doctors and favorably received by patients. .,www.i
36、vy-,E-mail: ; Tel: 02151370992,Wang et al., Neuroscience Letters 382:236-241, 2005 Acupuncture, a pearl in the Traditional Chinese Medicine, has been shown to bring about functional recovery after spinal cord injury, it has been widely used by doctors and favorably received by patients. .,www.ivy-,E
37、-mail: ; Tel: 02151370992,南宋末年，金兵大举入侵中原，朝廷昏聩无力，百姓生灵涂炭。话说嵩山脚下一对杨姓夫妇，年过半百，膝下尚无子嗣。,www.ivy-,E-mail: ; Tel: 02151370992,海上起了风暴，老约翰还是开着破船驶离了港湾。,南宋末年，金兵大举入侵中原，朝廷昏聩无力，百姓生灵涂炭。话说嵩山脚下一对杨姓夫妇，年过半百，膝下尚无子嗣。,www.ivy-,E-mail: ; Tel: 02151370992,Acupuncture, a pearl in the Traditional Chinese Medicine, has been show
38、n to bring about functional recovery after spinal cord injury, it has been widely used by doctors and favorably received by patients. .,Acupuncture expedites the functional recovery after spinal cord injury.,www.ivy-,E-mail: ; Tel: 02151370992,文化差异,www.ivy-,E-mail: ; Tel: 02151370992,Abstract The pr
39、esent study examined the role of dopamine D4 receptor on prepulse inhibition in rats. Gating deficit was induced pharmacologically using ketamine. Rats then received daily treatment with the D4-selective antagonist CP-293,019 vs. saline. ,www.ivy-,E-mail: ; Tel: 02151370992,www.ivy-,Abstract Abberan
40、t information processing (e.g., gating deficit) is the basis of many cognitive deficits in schizophrenia. Since dopamine D4 receptor is elevated in the brain of schizophrenia patients, we examined whether D4 receptor antagonism could alleviate gating deficit in a rat model. Prepulse inhibition was d
41、isrupted .,E-mail: ; Tel: 02151370992,摘要缺乏 “故事”情节,www.ivy-,E-mail: ; Tel: 02151370992,Effects of nifedipine on blood pressure in patients with primary hypertension vs. healthy controls,www.ivy-,E-mail: ; Tel: 02151370992,Effects of nifedipine on blood pressure in patients with primary hypertension v
42、s. healthy controls,Nifedipine decreases blood pressure in patients with primary hypertension but not in healthy controls,www.ivy-,E-mail: ; Tel: 02151370992,标题信息量太小,www.ivy-,E-mail: ; Tel: 02151370992,The study is potentially interesting and may in principle be suitable for this Journal. However, t
43、he paper is poorly presented and has little compliance with the format of our Journal. I have had a policy of greatly encouraging and accepting manuscripts from China, but the current widespread attitude of sending over manuscripts that are not properly prepared is being counterproductive, and it is not right that you should expect that other scient