《医药学论文-肝癌伴门静脉癌栓的治疗进展.txt》由会员分享，可在线阅读，更多相关《医药学论文-肝癌伴门静脉癌栓的治疗进展.txt（4页珍藏版）》请在三一文库上搜索。
1、 (hepatocellular carcinomaHCC)İ(portal vein tumor thrombiPVTT)PVTT 1 HCC1Child?Pugh AB Fukuda21948.5%Konishi3PVTT PVTT棺B 41295.4%47.0%20.0% 2 (drug delivery systemDDS) DDS52鷢 DDS(HAI)(PVI)(DDS)()PVTTAndo65?FU48HCCPVTT(hepatic arterial infusion chemotherapyHAIC)14PVTT34PVTT419(=48%)123545%31%25%11%23
2、2531.6(8.376.9)5.4(1.929.0)(P0.001)(P=0.021)71384飺14411964(transcatheter arterial chemoembolizationTACE)(hepatic artery infusionHAI)()(portal vein infusionPVI)13.40.512353.7%37.6%30.7%14.0%3.57.110.33(P0.05)滯 3 (transcatheter arterial chemoembolizationTACE) PVTTTACE PVTT8TACE Chung9TACE110PVTTTACE31
3、1230%18%10TACE11Katsumori12HCCPVTT0.51267%44%22% TACETACE13TACE 4 90%PVTTPVTTPVTTPVTT 1438PVTTB68.4%76.3%1373.7%18.4%PVTT15472TACE黼612243698.9%84.3%46.7%4.2%(P0.01)黼(P0.05) 5 (percutaneous ethanol injectionPEI) PVTTPEI16PEI590% TACETACEPEI PEIBPEI 1718PVTT38.9%İ44.4%16.7%PEIChan181PVTT18Yantamoto195
4、0HCCPVTTTACE 12B100%/90%12392.5%57.5%20% PEIPVTT 6 PVTTPVTT20Yamakado2021PVTT25.37.4mmHg22.46.6mmHg(P0.01)112.415TACE0.51264.2%29.2%29.2% 7 ( ultrasonic disruption)仯DNA21-22230100%23.2 cmH2O14.3 cmH2O1.8 h8.0 h鷢24Walker?256 羵塢鷢SG2+M绯23 8 TACE2526114060 Gy5(45%)12155%嶨TACEPVTT Yamada27PVTT(60 Gy)TACE
5、 19HCCPVTT57.9%1240.6%10.2%7.0PVTTHuang2841HCCPVTTTACEPVT101784PVTT(P=0.001) HCCPVTTPVTTPVTT30PVTT3520%029PVTTPVTT 1 . J. 200526(3)273-275.2 Fukuda S Okuda K Imamura M et al. Surgical resection combined with chemotherapy for advanced hepatocellular carcinoma with tumor thrombusreport of 19 casesJ. S
6、urgery2002131(3)300-310.3 Konishi M Ryn M Kinoshita T et al. Surgical treatment of hepatocellular carcinoma with direct removal of the tumor thrombus in the main portal reinJ. Hepatogastroenterology200148(41)1421.4 . (25)J. 199414(1)18-19.5 . (180)J. 199810(4)178-180.6 Ando E Tanaka M Yamashita F et
7、 al. Hepatic arterial infusion chemotherapy for advanced hepatocellular carcinoma with portal vein tumor thrombosisanalysis of 48 casesJ. Cancer200295(3)588-595.7 . J. 200341(11)801-804.8 Ralls PW. Color Doppler sonography of the hepatic artery and portal venous systemJ. AJR1990155(3)517-520.9 Chung
8、 JW Park JH Han JK et al. Hepatocellular carcinoma and portal vein invasion results of treatment with transcatheter oily chemoembolizationJ. Am J Radiol1995165(2)315-321.10 Trinchet JC Ganne?Carrie N Beangrand MI. Intraarterial chemoembolization in patients with hepatocellular carcinoma1J. Hepatogas
9、troenterology199845(suppl 3)1242.11 Terayama N Miyayama S Tatsu H et al. Subsegmental transcatheter arterial embolization for hepatocellular carcinoma in the caudate lobeJ. J Vasc Interv Radiol19989(3)501-508.12 Katsumori T Fujita M Satoh O et al. Effective segmental chemoembolization of advanced he
10、patocellular carcinoma with tumor thrombus in the portal veinJ. Cardiovasc Intervent Radiol199518(4)217-221.13 Asaki Y Imaoka S Kasugai H et al. A new approach to chemoembolization therapy for hepatoma using ethiodized oilcisplatinand gelatin spongeJ. Cancer198760(6)1194-1203.14 . J. 19997(1)13-14.1
11、5 . J. 200322(8)693-697.16 . 268J. 200120(3)1471.17 . J. 200110(2)81-83.18 Chan Mk Kwork PC Chan SC et al. PEI as a possible curative treatment for malignant portal vein thrombosis in hepatocellular carcinomaJ. Cardiovasc Intervent Radiol199922(4)3261.19 Yantamoto K Masuzawa H Kato M et al. Evaluati
12、on of combined therapy with chemoembolization and ethanol injection for advanced hepatocellular carcinomaJ. Semin Oncol199724(suppl 6)50-55.20 Yamakado K Tanaka N Nakatsuka A et al. Clinical efficacy of portal vein stent placement in patients with hepatocellular carcinoma invading the main portal ve
13、inJ. J Hepatol199930(4)660-668.21 Liebeskind D Bases R Koenigsberg M et al. Morphological changes in the surface characteristics of cultured cells after exposure to diagnostic ultrasoundJ. Radiology1981138(2)419-423.22 Sacks PG Miller MW Sutherland RM. Response of multicell spheroids to 1?MHz ultras
14、onic irradiationcavitation?related damageJ. Radiation Res198393(3)545-559.23 . J. 200015(1)24-26.24 . J. 20055(2)119-121.25 Lin DY Lin SM Liaw YF. Non?surgical treatment of hepatocellular carcinomaJ. J Gastroenterol Hepatol199712(9-10)s319-328.26 壬. J.2003184251256.27 Yamada K Izaki K Sugimoto K et
15、al. Prospective trial of combined transcatheter arterial chemoembolization and three? dimensional conformal radiotherapy for portal vein tumor thrombus in patients with unresectable hepatocellular carcinomaJ. Int J Radiat Oncol Biol Phys200357(1)113-119.28 Huang CJ Lian SL Chen SC et al. External beam radiation therapy for inoperable hepatocellular carcinoma with portal vein thrombosisJ. Kaohsiung J MedSci200117(12)610-614.29 Fan J Wu ZQ. Multimodality treatment in hepatocellular carcinoma patients with tumor thrombi in portal veinJ. Gastroentarol20017(1)28-32.