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1、2-巯基噻吩7774-74-5（2-mercaptothiophene 774-74-5）Our company produces the following products:Please contact 06325813522 155892969902-thiopheneChinese name: 2-thiophenolEnglish name: 2 - MercaptothiopheneThienylmercaptanThiophene - 2 - thiol2 - ThienylmercaptanMolecular structure:Molecular formula: C4H4S
2、2Molecular weight: 116CAS landing number: 7774-74-5Physical and chemical properties: the appearance is colorless or light yellow oily liquid, easy to oxidize in air, very small dissolve in water, soluble in ethanol and other organic flux.Density: 1.24Boiling point: 129 CFlash: 66 CContent: more than
3、 98%Sensory characteristics: unpleasant burning, burning, and sulfur.Packing: 100g/bottle, 1kg/bottle, 10kg/barrel, 25kg/pailStorage: sensitive to light and air, sealed to avoid light preservation.Darbika group ester (API)Dabigatran etexilateEnglish alias Pradaxa, bibr-1048ms, bibr-10482 - 3 - chemi
4、cal name 4 - (f oxygen) carbonyl amino of aminomethyl phenyl amino) methyl 1 - methyl - 1 - h - benzene and imidazole - 5 - base carbonyl (pyridine - 2 -) amino propionic acid ethyl esterEnglish chemical name: N - 2 - (4 - N - (Hexyloxycarbonyl) amidino phenylaminomethyl - h - 1 - methyl - 1 benzimi
5、dazol - 5 - ylcarbonyl - N - (2 - pyridyl) - beta - alanine baton rouge esterThe CAS number 211915-06-9Chemical formula C34H41N7O5(627.74)Character: colorless solid,Melting range of 126.4 127.8 structuredUSES:Darby and ester group is the forefront of a new generation of oral anticoagulant drugs (DTI
6、s) direct thrombin inhibitor, on acute and chronic thromboembolic disease prevention and treatment of the need to meet clinical needs.+ + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + +N - (4-cyanophenyl) glycine2 - (4 - Cyanoph
7、enylamino) acetic acidChinese name N - (4-cyanophenyl) glycine (dabiega intermediate - 1)English name N - (4 - Cyanophenyl) glycine2 - (4 - Cyanophenylamino alias) acetic acidProduct name N - (4-cyanophenyl) glycineMolecular formula C9H8N2O2The molecular weight of 176.17Content: 98%Appearance: white
8、 solidCAS login number 42288-26-6+ + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + +Chinese name: 3 - (4 - (methyl amino) - 3 - nitro - N - (pyridine - 2-base) benzoyl - benzoyl - ethyl - propionate (intermediate - 2)English name N - 4 - (methylamino) -3 - nitrobenzoyl -n-2-pyridinyl
9、 - alanine ethyl ester CAS RN 429659-01-8Molecular formula C18H20N4O5The molecular weight of 372.3752Appearance: white to class white powderCAS: 429659-01-8Specifications: 98.0%+ + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + +Product name: 4-methylamino-3-nitrobenzoic acid (dab i
10、ntermediate - 3)English 4 Methylamino - 3 - nitrobenzoic acidChemical name: 4-methylamino-3-nitrobenzoic acidPurpose: dabija group intermediateAppearance: white powderContent: 99%Heavy metal: 10ppmSpecification: pharmaceutical gradeCAS: 41263-74-5+ + + + + + + + + + + + + + + + + + + + + + + + + + +
11、 + + + + + +Chinese name 3 - (pyridine-2-base amino) ethyl propionate (intermediate - 4)Chinese alias N - 2 - pyridine - propyl - alanineEnglish baton rouge 3 - (2 - ylamino pyridin -) propanoateCAS) : 103041-38-9Subtype: C10H14N2O2Subquantity: 194.23036Specifications: 99%Packing: 1 kg 5kg/pail+ + +
12、 + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + +N - 4-methylamino-3-aminobenzyl N - 2 - pyridinyl - b - alanine ester (dabiega intermediate - 5)English 3 - (3 - amino - 4 - methylamino - benzoyl) pyridin - 2 - yl - amino -Propionic acid baton rouge esterCAS 21
13、2322-56-0EINECS no.C18H22N4O3 by childrenAmount of 342.3923 points+ + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + +Chinese N - 2 - (4 - cyano benzene) amine methyl - 1-5 - methyl - 1 h benzene and imidazole carbonyl amino benzene acyl N - 3-2 - pyridyl - b - alanine ethyl ester (darb
14、y group of ester intermediates - 6)English baton rouge 3 - (2 - (4 - cyanophenylamino) methyl) - 1 - methyl - N - (pyridin - 2 - yl) - 1 h - benzo d imidazole - 5 - carboxamido) propanoateCAS RN) 211915-84-3EINECS no.C27H26N6O3 by childrenAmount of 482.5337 pointsUse of a group of intermediates+ + +
15、 + + + + + + + + + + + + + + + + + + + + + + + + + + + +Apixaban (API)The chemical name4, 7-4 h - 1 - (4 - methoxy phenyl) - 7 - oxygen generation - 6 - 4 - (2 - oxygen generation - 1 - piperidine base) phenyl - 1 h - pyrazole and 3, 4 - C pyridine - 3 - formamideChemical name of English1 - (4 - Met
16、hoxyphenyl) - 7 - oxo - 6 - 4 - (2 - oxopiperidin - 1 - yl) phenyl - 4, 7 - tetrahydro - 1 h - pyrazolo 3, 4 - c pyridine - 3 - carboxamideCAS: 503612-47-3USES:Heart cerebrovascular antithrombotic.Reduce the risk of cardiovascular events, stroke and death in ACS patients; But compared with the contr
17、ol group, there was no statistical significance. Therefore, the high safety and efficacy of Apixaban has attracted wide attention in the industry.+ + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + +Chinese name 6 - (4 - iodiphenyl) - 1 - (4 - methoxyphenyl) -7 - oxygen generation - 4,
18、 5, 6, 7-4 hydro-1h-pyrazole and 3, 4 - c pyridine-3-carboxylic acid ethyl ester (use: apperacan intermediate - 1)English name Ethyl alcohol 6 - (4 - methoxyphenyl) -7 - oxo-4, 5, 6, 7-tetrahydro-1h-pyrazolo 3, 4 - c pyridine - 3 - carboxylateMolecular formula C22H20IN3O4The molecular weight of 517.
19、32CAS login number 473927-64-9+ + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + +Chinese name (4 - methoxyphenyl) hydrazid ethyl chloroacetate (use: apperazan intermediate - 2)English name (Z) - baton rouge 2 - chloro - 2 - (2 - (4 - methoxyphenyl) hydrazono) acetateChinese ali
20、as 2-chloro-2 - 2 - (4-methoxy phenyl) anhydra ethyl acetateCAS RN 27143-07-3EINECS no.C11H13ClN2O3 by childrenAmount of 256.6855 points+ + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + +Chinese name: 1 - (4 - iodiphenyl) -3 - morpholine - 5, 6-dihydropyridine - 2 (1H
21、) - ketone (use: apperacan intermediate - 3)Chinese synonyms: 1 - (4 - iodiphenyl) -3 - morpholine - 5, 6-dihydropyridine - 2 (1H) - ketoneEnglish name: 1 - (4 - iodophenyl) - 3 - morpholino - 5, 6-dihydropyridin - 2 (1H) - oneCAS no. : 473927-69-4Molecular formula: C15H17IN2O2Molecular weight: 384.
22、21215+ + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + +Chinese name: 1 - (4-iodophenyl) -2 - piperidone (purpose: apezzaran intermediate - 4)Chinese synonyms: 1 - (4 - iodiphenyl) - 2 - piperidoneEnglish name: 1 - (4 - iodo-phenyl) - PIPERIDIN - 2 - ONE1 - (4 - iodo-phenyl
23、) - PIPERIDIN - 2 - ONE; 1 - (4 - Iodophenyl) - 2 - piperidinone; Apixaban IICAS no. : 385425-15-0Molecular formula: C11H12INOMolecular weight: 301.12355+ + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + +Chinese name: 4, 5, 6,7-4 h - 1 - (4 - methoxy phenyl) - 6 - (
24、4 - nitro phenyl) - 7 - oxygen generation of 1 h - pyrazole and 3, 4 - C pyridine - 3 - carboxylic acid ethyl ester (o use: pp shaaban intermediates - 5)(4 - methoxyphenyl) - 6 - (4 - nitrophenyl) -7 - oxo - 4, 5, 6, 7-tetrahydro-1h-pyrazolo 3, 4 - c pyridine - 3 - carboxylateCAS no. : 536759-91-8Mo
25、lecular formula: C22H20N4O6Molecular weight: 436.4174+ + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + +5 or 6 - dihydro - 3 - (4 - morpholine) - 1 - (4 - nitro phenyl) - 2 (1 h) - pyridine ketone (o use: pp shaaban intermediates - 6)English 3 - morpholino - 1 - (4 - nitrophenyl) - 5
26、, 6 - dihydropyridin - 2 (1 h) - oneCAS no. : 503615-03-0Molecular formula: C15H17N3O4Molecular weight: 303.31318+ + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + +Chinese name: 1 - (4-nitrophenyl) - 2 - piperidione (application: apypazan intermediate - 7)English 1 - (4 - nitrophenyl)
27、piperidin - 2 - oneCAS no. : 38560-30-4Molecular formula: C11H12N2O3+ + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + +Product name: 1 - (4 - methoxy phenyl) - 7 - oxygen generation - 6 - 4 - (2 - oxygen generation piperidine - 1 - base) phenyl - 4, 7-4 h - 1 h - pyrazole a
28、nd 3, 4 - c pyridine - 3 - carboxylic acid ethyl ester (o use: pp shaaban intermediates - 8)(4 - methoxyphenyl) - 6 - (4-aminophenyl) -7 - oxo - 4, 5, 6, 7-tetrahydro-1h-pyrazolo 3, 4 - c pyridine - 3 - carboxylateCAS no. : 503615-07-4Molecular formula: C22H22N4O4Molecular weight: 406.4410+ + + + +
29、+ + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + +Sunitinib (Sutent) (API)CAS No. : 557795-19-4EINECS: secure dataSubtype: C26H31FN4O6Subquantity: 398.47USES:The latest targeted therapy drugs, dual-channel, multi-target tyrosine kinase inhibitorsSunitinib (sotan) - kidney cancer,
30、gastrointestinal stroma, non-small cell lung cancer, new drug for liver cancer.+ + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + +Chinese name: 2, 4-dimethyl-5-aldehyd-pyrrol-3-carboxylic acid (use: dimethylamine intermediate - 1)English 5 - formyl - 2, 4 - dimethyl - 1 h - p
31、yrrole - 3 - carboxylic acidCAS No. : 253870-02-9Subtype: C8H9NO3Score: 167.16+ + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + +Chinese name: n-methyl - 4-chloropyridine - 2 - formamide (sorafenib intermediate - 1)English 4 - chloro - (2 - pyridyl) - N - methylcarboxamideCAS No. :
32、 220000-87-3Subtype: C7H7ClN2OAmount: 170.60The introduction of SORAFENIB (SORAFENIB) is applicable to: 1. Treatment of terminal renal cell carcinoma that cannot be operated on. 2. Treatment of primary hepatic cell carcinoma that cannot be operated or transferred remotely.+ + + + + + + + + + + + + +
33、 + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + +Chinese 4 - 4-hydroxy-2-pyridinyl) benzene nitrile (the intermediate of the anti-hiv drug lipiverin)English 4 - (4 - Hydroxy - 2 - pyrimidinyl) amino benzonitrileCAS No. : 189956-45-4Subtype: C11H8N4OSubquantity: 212.21Molecular f
34、ormula:The new drug, which was approved by the FDA on May 20, 2011, is an anti-hiv drug.+ + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + +Chinese 2-methyl-4-pyrimethadone (the middle body of the anti-hiv drug, t
35、he lepiverine).2-4 - pyrimidinol Methylthio - in EnglishMolecular formula: C5H6N2OSMolecular weight: 142.18EINECS: 227-274-6CAS 5751-20-2+ + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + +Bosutinib (CAS No. 380843-75-4)Chinese alias: bosutini
36、; 4 - (2, 4 - dichloro - 5 - methoxy phenyl) amino - 6 - methoxy - 7 - 3 - (4 - methyl - 1 - piperazine) oxygen radicals c - 3 - quinoline nitrileEnglish 4 - (2, 4 - dichloro - 5 - methoxy - phenyl) amino - 6 - methoxy - 7 - 3 - (4 - methylpiperazin - 1 - yl) propoxy quinoline - 3 - carbonitrileIntr
37、oduction to theThis is a tyrosine kinase inhibitor that inhibits the tyrosine kinase that stimulates abnormal white blood cells in patients with leukemia.+ + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + +Chinese 2 - (3 - chloropropyl) - 1 - methoxy - 4-nitroben
38、zene (intermediate - 1)English 2 - (3 - Chloropropoxy) - 1 - methoxy - 4 - nitrobenzeneCAS (92878-95-0Molecular formula: C10H12ClNO4Molecular weight: 245.6596Chemical properties: density: 1.268 g/cm3Boiling point: 388.3 C at 760 mmHgFlash: 188.6 C+ + + + + + + + + + + + + + + + + + + + + + + + + + +
39、 + + + + + + + + + + + + + + + + + + + + + + + + + +Chinese name 3 - methyl - 1 - (3, 4-dimethylphenyl) - 2 - pyrazolino-5-ketone (ecquopopa intermediate - 1)English name 3 - dimethylphenyl (3, 4 - dimethylphenyl) - 2 - pyrazolin - 5 - oneCAS (18048-64-1Molecular formula: C12H14N2OMolecular weight:
40、202.2524Chemical properties: density: 1.13 g/cm3Boiling point: 390.1 C at 760 mmHgFlash: 189.7 CIntroduction to theThrombocytopenia of patients with chronic idiopathic thrombocytopenic purpura (ITP) patients with chronic idiopathic thrombocytopenic purpura (ITP) were treated with glucocorticosteroid
41、 and immunoglobulin.+ + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + +English 1 - (3, 4 - Dimethylphenyl) - 4, 5 - dihydro - 3 - methyl - 5 - oxo - 1 h - pyrazole - 4 - carboxaldehyde (ai curvelet palmer intermediates - 2)Molecular formula: C13H14N2O2CA
42、S (473681-77-5Introduction to theThrombocytopenia of patients with chronic idiopathic thrombocytopenic purpura (ITP) patients with chronic idiopathic thrombocytopenic purpura (ITP) were treated with glucocorticosteroid and immunoglobulin.+ + + + + + + + + + + + + + + + + + + + + + + + + + + + + + +
43、+ + + + + + + + + + + +The Chinese imatinibEnglish imatinibCAS (152459-95-5Chemical name of 4 - (4 - methyl - 1 - piperazine) methyl - N - (4 - methyl - 3 - (4 - (3 - pyridyl) - 2 - pyrimidine base amino benzamide phenylMolecular formula C29H31N7OThe molecular weight of 493.60Introduction to theImat
44、inib is a drug that treats common types of cancer. It is used to treat chronic myelogenous leukemia (CML), gastrointestinal stroma (gastrointestinal stroma) and other diseases. By 2011, the drug had been approved by the FDA to treat 10 different cancers. For chronic myeloid leukemia, tyrosine kinase
45、 ABL is locked in its activation form. It leads to the abnormal phenotype of chronic myeloid leukemia: hyperproliferation and high leukocyte count. Imatinib binds with tyrosine kinase activity and blocks its activity.+ + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + + +
46、Chinese vadaraniEnglish vatalanibCAS 212141-51-0Molecular weight (MW) : 419.73Chemical formula: C20H15ClN4? 2 HCLSolubility: DMSO is greater than 28mg/mL Water or greater than 10mg/mL: purity 99%Stability: the at - 20 for 2 yearsIntroduction to theValladani is a new multitarget anticancer drug,It can effectively inhibit vascular endothelial growth factor receptor (VEGFR) family member, platelet derived growth factor receptor beta (PD