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1、Lab Automation Markets 5th THE WORLDWIDE MARKET FOR LAB AUTOMATION A MARKET INTELLIGENCE ANALYSIS OF MANUFACTURERS AND SUPPLIERS OF LAB AUTOMATION SYSTEMS FEBRUARY 2013 The Worldwide Market for Lab Automation has been prepared by Kalorama Information. We serve business and industrial clients worldwi
2、de with a complete line of information services and research publications. Kalorama Information Market Intelligence Reports are specifically designed to aid the action-oriented executive by providing a thorough presentation of essential data and concise analysis. Author: Joseph A. Constance Publicat
3、ion Date: February 2013 COPYRIGHT 2013 Kalorama Information a division of MarketR, Inc. Copyright 2013 Kalorama Information Copyright 2013 Kalorama Information TABLE OF CONTENTS 1.0 EXECUTIVE SUMMARY .1? 1.1 Indispensable Technology 1? 1.1.1 Competitive Pressures for the Clinical Lab . 3 Key Process
4、es to Automate . 7? 1.1.2 Automation Speeds Drug Discovery . 6 Variety of Processes . 7? 1.2 Trending Toward Customization, Speed and Standardization 8? 1.2.1 Miniaturization 10? 1.3 Advantages and Trade-Offs . 11? 1.4 Market Overview 13? 2.0 INTRODUCTION17? 2.1 Overview 18? 2.1.1 Benefits of Automa
5、tion 16 2.3 The Drug Discovery Laboratory . 18? 2.2 The Clinical Laboratory 17? 2.2.1 The Labor Challenge . 17? 2.3 The Drug Discovery Laboratory . 18? 2.3.1 Increasing Throughput . 18? 2.4 New Range of Tools. 20? 2.5 Planning and Management 20? 2.6 Key Issues 21? 2.6.1 Issues in the Clinical Labora
6、tory . 21? 2.6.2 Issues in the Drug Discovery Laboratory 22? 2.6.3 Work Flow . 23? 2.6.4 Labor Issues . 26? 2.6.5 Operating Costs . 29? 2.6.6 Compatibility . 30? 2.7 Targets for Automation 33? 2.7.1 Liquid Handling . 34? Copyright 2013 Kalorama Information Copyright 2013 Kalorama Information 2.7.2 T
7、est Tube Processing . 34? 2.7.3 Decapping 35? 2.7.4 Microplates and Microarrays . 36? 2.8 Health Care Trends Impacting Automation . 37? 2.8.1 Affordable Care Act Tax Impact . 38? 2.9 Automation Equipment Trends . 39? 2.9.1 Miniaturization 40? 2.9.2 Standards, Connectivity and Integration 41? 2.10 To
8、tal Lab Automation . 43? 2.11 Modular Automation 45? 2.12 FDA Regulation . 48? 2.13 Reimbursement . 49? 2.13.2 Assessing Outcomes 50 ? 3.0 ISSUES AND TRENDS .53? 3.1 Danaher Acquires Beckman Coulter 53? 3.2 Roche Acquisition . 54? 3.3 Pfizer, UCB Partnership Speeds Drug Discovery 54? 3.4 Labotix Acq
9、uisition . 55? 3.5 Life Technologies Acquires BioTrove . 55? 3.6 PerkinElmer Acquires Caliper 56? 3.7 BD Acquires Kiestra . 56? 3.8 Labotix, NoemaLife Collaborate to Optimize Efficiency 57? 3.9 Fully Automated System 58? 3.10 Expanding to Laboratory Automation 58? 3.11 Partnering 59? 3.12 Co-Develop
10、ment, Co-Marketing, Co-Selling 59? 3.13 Automation Solves Sample Lysis Bottleneck 60? 3.14 Automation for Secondary Screening . 60? 3.15 Higher-Throughput Drug Discovery Automation . 60? 3.16 Blood Sciences Laboratory Automation . 61? 3.17 Optimizing Liquid Handling 61? Copyright 2013 Kalorama Infor
11、mation Copyright 2013 Kalorama Information 3.18 Bench top Platform Controls Automation 62? 3.19 Integrated Laboratory Automation. 62? 3.20 Automated Stem-Cell Picker 63? 4.0 MARKETS .65? 4.1 A World Market Perspective . 65? 4.1.1 Merges and Acquisitions Alter the Commercial Landscape 66? 4.2 Clinica
12、l Lab Automation Markets . 68? 4.2.1 Sample Transport Systems. 74? 4.2.2 Storage-Retrieval Systems . 78? 4.2.3 Work Stations 81? 4.2.4 Specimen Handling Systems . 84 4.2.4 LIMS 87? 4.3 Drug Discovery Lab Automation Markets . 89? 4.3.1 Plate Readers . 94 4.3.2 Automated Liquid Handling Systems 94? 4.
13、3.3 Robotics . 102? 4.3.4 Dissolution Testing 108? 4.3.5 LIMS 111 4.3.6 Storage-Retrieval.Systems . 115 4.4 Market Share in Lab Automation . 116? ? 5.0 COMPANY PROFILES 121? 5.1 Abbott Diagnostics 121? 5.2 Agilent Technologies Inc. . 123? 5.3 Ai Scientific 126? 5.4 Aurora Biotechnologies (Nexus). 12
14、7? 5.5 Beckman Coulter Inc. . 129? 5.6 BD (Becton, Dickinson and Company) . 131? 5.7 BioTrove . 133? Copyright 2013 Kalorama Information Copyright 2013 Kalorama Information 5.8 Brooks Automation Inc. . 134? 5.9 Caliper Life Sciences . 135? 5.10 Dynacon Inc. 137? 5.11 Eppendorf AG . 138? 5.12 Hamilto
15、n Storage Technologies Inc. 139? 5.13 InnovaSystems Inc. . 141? 5.14 Labotix Automation Inc. 142? 5.15 LabVantage Solutions Inc. . 143? 5.16 Molecular Devices . 144? 5.17 Motoman Robotics Division . 146? 5.18 Olympus Corp. 148? 5.19 Peak Analysis and Automation 150? 5.20 PerkinElmer Life and Analyti
16、cal Sciences Inc. 151? 5.21 F. Hoffmann-La Roche Ltd. . 153? 5.22 RTS Life Science . 155? 5.23 Siemens Healthcare . 157? 5.24 Sotax . 160? 5.25 SSi Robotics . 162? 5.26 TAP Biosystems . 163? 5.27 Tecan Group Ltd. 165? 5.28 ThermoFischer Scientific Inc. 167? 5.29 Wako Automation . 170? 5.30 Xiril AG
17、172? ? Copyright 2013 Kalorama Information Copyright 2013 Kalorama Information LIST OF EXHIBITS ?1.0 EXECUTIVE SUMMARY ? Exhibit 1: Significant Trends in the Laboratory Automation Market . 9? Exhibit 2: Lab Automation Market, 2013, 2015, 2017 . 12? Exhibit 3: Regional Breakout of Clinical Lab Automa
18、tion Market . 13? 2.0 INTRODUCTION? Exhibit 4: Laboratory Automation Issues . 23? Exhibit 5: Median Annual Earnings for Lab Technologists, May 2010 . 27? Exhibit 6: Median Annual Earnings for Lab Technicians, May 2010 27? Exhibit 7: Median Hourly Wages for Lab Technologists and Technicians, 2010 . 2
19、8 ? 4.0 MARKETS? Exhibit 8: World Market for Clinical Lab Automation Systems, 2012-2017 71? Exhibit 9: World Market for Clinical Lab Automation Systems, 2012-2017 by Geographic Segment (US, Europe, BRIC, Japan, ROW) 72? Exhibit 10: World Medical Market for Clinical Lab Automation Systems 2013 by Geo
20、graphic Segment (US, Europe, BRIC, Japan, ROW) . 73? Exhibit 11: Clinical Laboratory Automation Systems, US Installed Base Major Systems, 2012-2017 . 74? Exhibit 12: World Market for Clinical Lab Sample Transport Automation Systems, 2012- 2017 77? Exhibit 13: World Market for Clinical Lab Sample Tra
21、nsport Automation Systems by Geographic Segment (US, Europe, BRIC, Japan, ROW) 78? Exhibit 14: World Market for Clinical Lab Storage-Retrieval Systems 80? Exhibit 15: World Market for Clinical Lab Storage-Retrieval Systems, 2012-2017 by Geographic Segment (US, Europe, BRIC, Japan, ROW) . 81? Exhibit
22、 16 World Market for Clinical Lab Automation Work Stations, 2012-2017 . 83? Copyright 2013 Kalorama Information ? Copyright 2013 Kalorama Information Exhibit 17: World Market for Clinical Lab Automation Work Stations 2012-2017: By Geographic Segment . 84? Exhibit 18: World Market for Clinical Lab Au
23、tomation Specimen Handling Systems, 2012-2017 86? Exhibit 19: World Market for Clinical Lab Automation Specimen Handling Systems, 2012-2017: By Geographic Segment . 84? Exhibit 20: Market for Clinical Lab Automation LIMS, 2012-2017 89? Exhbit 21: World Market for Drug Discovery Laboratory Automation
24、 Systems, 2012-2017 92? Exhibit 22: World Market for Drug Discovery Laboratory Automation Systems, 2012-2017 By Geographic Segment (US, Europe, BRIC, Japan, ROW) . 93? Exhibit 23: World Medical Market for Drug Discovery Lab Automation Systems by Geographic Segment (US, Europe, BRIC, Japan, ROW) 94?
25、Exhibit 24: World Market for Drug Discovery Lab Automation Plate Readers. 97? Exhibit 25: World Market for Drug Discovery Lab Automation Plate Readers , 2012-2017: by Geographic Segment (US, Europe, BRIC, Japan, ROW) . 98? Exhibit 26: World Market for Drug Discovery Automated Liquid Handling Systems
26、 101? Exhibit 27, World Market for Drug Discovery Lab Automation Systems Automated Liquid Handling Systems, 2012-2017 by Geographic Segment (US, Europe, BRIC, Japan, ROW) 102? Exhibit 28: World Market for Drug Discovery Lab Automation Systems: Robotic Systems, 2012-2017 . 106? Exhibit 29: World Mark
27、et for Drug Discovery Lab Automation Systems, Robotic Systems, 2012-2017, by Geographic Segment (US, Europe, BRIC, Japan, ROW) . 107? Exhibit 30: World Market for Drug Discovery Dissolution Testing Systems 108? Exhibit 31: World Market for Drug Discovery Dissolution Testing Systems, 2012-2017 by Geo
28、graphic Segment (US, Europe, BRIC, Japan, ROW) . 109? Exhibit 32: World Market for Drug Discovery LIMS, 2012-2017 115? Exhibit 33: World Market for Drug Discovery Storage-Retrieval Systems, 2012-2017 117? Exhibit 34: World Market for Drug Discovery Storage-Retrieval Systems 2012-2017 by Geographic S
29、egment(US, Europe, BRIC, Japan, ROW) 118? Exhbiit 35: Market Share By Vendor, Lab Automation Market . 119? ? 1.0 Executive Summary Automation is finally making a significant impact in health care, especially in laboratories where systems are improving work flow and adding speed and efficiency. Labor
30、atory automation systems and technologies incorporate devices, software or processes that improve the efficiency of a laboratory. Lab automation technology includes integrated hardware and software designed to process and analyze specimens. Over the years, many laboratories in North America, Europe
31、and elsewhere have installed fully functional automation systems, as well as individual automated systems. But there are many laboratories that have not automated or which have automated only to a limited extent. 1.1 INDISPENSABLE TECHNOLOGY Systems that automate are essential for laboratories facin
32、g difficult market competition. In the case of drug discovery, lab automation systems speed the identification of drug targets. Automation hardware can be installed in the form of a complete automation system total laboratory automation (TLA) - or as discreet hardware devices that perform specific t
33、asks modular automation. 1.0 Executive Summary Automation is finally making a significant impact in health care, especially in laboratories where systems are improving work flow and adding speed and efficiency. Laboratory automation systems and technologies incorporate devices, software or processes
34、 that improve the efficiency of a laboratory. Lab automation technology includes integrated hardware and software designed to process and analyze specimens. Over the years, many laboratories in North America, Europe and elsewhere have installed fully functional automation systems, as well as individ
35、ual automated systems. But there are many laboratories that have not automated or which have automated only to a limited extent. 1.1 INDISPENSABLE TECHNOLOGY Systems that automate are essential for laboratories facing difficult market competition. In the case of drug discovery, lab automation system
36、s speed the identification of drug targets. Automation hardware can be installed in the form of a complete automation system total laboratory automation (TLA) - or as discreet hardware devices that perform specific tasks modular automation. One: Executive Summary 2 Copyright 2013 Kalorama Informatio
37、n One: Executive Summary 2 Copyright 2013 Kalorama Information Laboratory automation systems improve the quality and efficiency of laboratory operations. These systems provide a solution to the demands for quality and staff shortages faced by todays clinical laboratories. On the drug discovery front
38、, lab automation has facilitated drug development by reducing the potential for error and by facilitating high throughput screening (HTS). Because the ability to test a large number of compounds quickly and efficiently offers a competitive advantage, HTS has become a key element in drug discovery. V
39、arious companies, offer instrumentation and systems for HTS, which incorporate homogeneous assay formats. With the advent of new technologies such as microarrays, microfluidics, and lab-on-a- chip, not only the throughput but the way in which data are generated is changing the face of drug discovery
40、 and clinical diagnostics. Among smaller laboratories and those with limited budgets, the trend continues toward implementing modular automation - small work cells that can be rapidly configured, installed, brought into operation, and reconfigured when the need arises. The benefits of automation in
41、the clinical laboratory include: replacing manual, potentially dangerous, error-prone steps with automated processes requiring minimal operator intervention. This approach can increase productivity, decrease turnaround time, improve staff safety, minimize errors, improve the handling of specimens, a
42、nd allow labs to reallocate personnel to more important and productive tasks. Furthermore, the rapid turnaround time for critical tests, the intra-laboratory tracking of specimens, and preventing errors in specimen aliquoting have a positive impact on patient safety. For drug discovery, bringing a n
43、ew drug to market has been both a very time- intensive, laborious and expensive undertaking. Thousands of compounds are typically identified in the drug discovery process, but only a few make it to clinical trials with human subjects. Developing and introducing a new drug to the market costs about $
44、1 billion and takes about 15 years. Given such lengthy development cycles and high research costs, big pharma is always interested in more cost-effective and timely approaches to drug discovery. Lab automation can be used throughout the pre-clinical drug discovery process, involving microtiter plate
45、s, automated analyzers, HTS, robotics and liquid handling systems, among other systems. The pipetting workstation - liquid handling - remains the cornerstone of lab automation and play a critical part in completing the automation process Automation is not always harnessed to lower labor costs, but a
46、lso to improve experimental accuracy and work flow efficiency. Automation also allows qualified One: Executive Summary 3 Copyright 2013 Kalorama Information One: Executive Summary 3 Copyright 2013 Kalorama Information researchers to properly analyze results or develop new areas for research rather t
47、han undertaking the laborious and repetitive manual steps of an experimental set-up. 1.1.1 Competitive Pressures for the Clinical Lab Many clinical laboratories are facing a number of issues that are challenging their ability to remain competitive including: the reduction of government reimbursement
48、 rates for laboratory tests, cost-restraint measures established by the managed care industry, and the continuing trend toward containment of national health care costs. With continuing cuts in government reimbursement rates for laboratory testing, along with cost-cutting measures adopted by the man
49、aged care industry, and the move to cut health care costs in general, clinical laboratories are exploring ways to improve productivity with smaller budgets. They are increasingly adopting laboratory automation systems to address the problems associated with an increase in volume for diagnostic tests, decreasing reimbursement rates, and a diminished labor pool. The contribution of lab automation to the clinical diagnostics industry continues to expand, with the entry of more suppliers into the market which are off